解沛忠 教授

E-mail: peizhongxie@njtech.edu.cn; peizhongxie0216@163.com

解沛忠，教授，南开大学博士，東京大学博士后。2014年11月加入南京工业大学，主要从事天然官能团原料绿色转化研究、碱土金属/光催化研究、生物偶联新方法探索。主持国家自然科学基金、江苏省自然科学基金面上/青年基金，获得江苏省“六大人才高峰”高层次人才资助，入选2021年江苏省青年科技创新“U35攀峰”系列提名人选称号。独立工作以来，以通讯作者在Nat. Commun. Chem. Sci. Green Chem. Org. Lett.等期刊发表论文30余篇，获得授权发明专利20余项，部分研究成果被Nat. Rev. Chem.等刊物专文亮点评述、被《中国科学报》等报道。讲授《有机化学》等课程，荣获“南工晨星奖教金”等教学奖励。指导的硕士生多人获得“国家奖学金”；指导的本科生毕业论文获得江苏省优秀本科毕业论文“二等奖”。

发表论文（Publications @ NJ Tech）：

35. Chengyang Ju, Xiaoyu Liu, Yanzhe Shi, Yinlei Zhang, Teck-Peng Loh, Peizhong Xie*, Organophotocatalytic Decarboxylative Allylation of Carboxylic Acids with Allylic Acetates. Org. Lett. 2025, 27, 11338. Org. Lett. 2025, 27, 11338.

34. Yanyu Lu, Kaiyu Yan, Yanzhe Shi, Cuiqing Gao, Yitao Zhu, Yinlei Zhang, Teck-Peng Loh, Peizhong Xie*, Lumiflavine-catalyzed, visible-light-driven allylation of cyclobutanone oximes: a sustainable approach to distally unsaturated nitriles. Org. Chem. Front. 2025, 12, 5947.

33. Mengxue Zheng, Yuting Gao, Xiaoyu Liu, Lei Zhang*, Yongming Tang, Teck-Peng Loh*, Peizhong Xie*, Organic Solvent-Free Synthesis of 3-Difluoroalkyl Phthalides. J. Org. Chem. 2025, 90, 11330. (Invited for special issue: Celebrating Nankai University’s Legacy of Excellence in Organic Chemistry).

32. Bohan Li, Daniel Paniroi Situmorang, Zhenguo Zhang, Raymond Tio, Peizhong Xie, Teck-Peng Loh*, Oxocarbenium Lewis Acid Complex: A Neutral Thiol-Specific Bioconjugation Reagent. Green. Synth. Catal. 2025, Doi: 10.1016/j.gresc.2025.06.010.

31. Zhenwei Zhang, Xu Tao, Chengyang Ju, Cuiqing Gao, Teck-Peng Loh*, Peizhong Xie*, Biocompatible C-S bond construction for diarylmethyl thioethers. Green. Synth. Catal. 2025, Doi: 10.1016/j.gresc.2025.03.002.

30. Yanli Yin, Fan Chen, Dong Chen, Peizhong Xie, Dongping Wang*, Teck-Peng Loh*, Iron-Photocatalyzed Decarboxylative Alkylation of Carboxylic Acids with Morita–Baylis–Hillman Acetates. Org. Lett. 2025, 27, 269.

29. Jingwei Hou, Xiaohong. Li, Kaiyu Yan, Lei Zhang*, Teck-Peng Loh*, Peizhong Xie*, Uracil-Cu(I) catalyst: allylation of cyclopropanols with Morita–Baylis–Hillman alcohols under water tolerant conditions. Chem. Sci. 2024, 15, 1143.

28. Xiaoyu Zhang, Fanyi Hou, Yinlei Zhang, Bowen Li, Peizhong Xie*, Teck-Peng Loh*, Decarboxylative Coupling of Ketoacids with Allylic Acetates. Org. Lett. 2024, 26, 10696.

27. Yinlei Zhang, Yanyu Lu, Chengyang Ju, Zhenwei Zhang, Dongping Wang, Shirui Wang, Peizhong Xie*, Teck-Peng Loh*, Photocatalytic Decarboxylative Allylation of α‑Amino Acids and Peptides under Metal-Free Conditions. Org. Lett. 2024, 26, 8121.

26. Mengxue Zheng, Wenxiu Gao, Lei Zhang, Kaiyu Yan, Zhenwei Zhang, Peizhong Xie*, Teck-Peng Loh*, Allylation of Lactol in Water. Org. Lett. 2024, 26, 10201.

25. Wubing Zeng, Xiaoyu Zhang, Yinlei Zhang, Shiji Xiao, Yongming Tang, Peizhong Xie*, Teck-Peng Loh*, Organophotoredox-Catalyzed Intermolecular Formal Grob Fragmentation of Cyclic Alcohols with Activated Allylic Acetates. Org. Lett. 2023, 25, 5869.

24. Yan Wang, Guangming Wu, Kaiyu Yan, Jiahang Qin, Rui Liu, Nanan Rong, Yongming Tang, Teck-Peng Loh, Peizhong Xie*, Sulfination of Unactivated Allylic Alcohols via Sulfinate−Sulfone Rearrangement Org. Lett. 2023, 25, 8895. (ACS Editors’ Choice)

23. Xiaoyu Zhang, Yinlei Zhang. Xiaohong Li, Bowen Li, Shiji Xiao, Yongming Tang, Peizhong Xie*, Teck-Peng Loh*, Fluoroalkylation of Activated Allylic Acetates through Radical−Radical Coupling: Organophotoredox/DABCO Catalytic System. Org. Lett. 2023, 25, 6863.

22. Wenxiu Gao, Dong Zhang, Xiaoyu Zhang, Xinying Cai, Peizhong Xie*, Teck-Peng Loh*, One-Pot and Unsymmetrical Bis-Allylation of Malononitrile with Conjugated Dienes and Allylic Alcohols,
Org. Lett. 2022, 24, 9355.

21. Wenxiu Gao, Dong Zhang, Xiaoyu Zhang, Xinying Cai, Peizhong Xie*, Teck-Peng Loh*, One-Pot and Unsymmetrical Bis-Allylation of Malononitrile with Conjugated Dienes and Allylic Alcohols,
Org. Lett. 2022, 24, 9355.

20. Huicong Xing, Meijuan Chen, Dong Zhang, Zhishuai Geng, Peizhong Xie*, Teck-Peng Loh*, Dehydrative Cross-Coupling for C−N Bond Construction under Transition-Metal-Free Conditions,
Org. Lett. 2022, 24, 5657.

19. Ju Qiu, Jingwei Hou, Zuolian Sun, Peizhong Xie*, Dehydrative and Decarboxylative Coupling of Alkynoic Acids with Allylic Alcohols,
Synthesis 2022, 54, 2787. (Invited Feature Article)

18. Xingying Cai, Huicong Xing, Ju Qiu, Bowen Li, Peizhong Xie*, Dehydrative Allylation of Alkenyl sp² C-H Bonds,
Org. Lett. 2021, 23, 4368.

17. Xiaobo Yang, Bowen Li, Huicong Xing, Ju Qiu, Teck-Peng Loh, Peizhong Xie*, Dehydrative allylation of P-H species under metal-free conditions,
Green Chem. 2021, 23, 1633.

16. Bowen Li, Wubing Zeng, Lin Wang, Zhishuang Geng, Teck-Peng Loh*, Peizhong Xie*, Visible-Light-Induced Trifluoromethylation of Allylic Alcohols,

Org. Lett. 2021, 23, 5253.

15. Shuangshuang Li, Ju Qiu, Bowen Li, Zuolian Sun, Peizhong Xie*, Teck-Peng Loh*, Practical allylation with unactivated allylic alcohols under mild conditions,
Org. Chem. Front. 2021, 8, 3354.

14. Huicong Xing, Peizhong Xie*, Construction of Benzothiophene Fused Pyrrolidone in Water under Catalyst-Free Conditions,
Chin. J. Org. Chem. 2021, 41, 431 (Invited Highlight).

13. Peizhong Xie*, Zuolian Sun, Shuangshuang Li, Xinying Cai, Ju Qiu, Weishan Fu, Cuiqing Gao, Shisheng Wu, Xiaobo Yang, Teck-Peng Loh*, Reciprocal-activation strategy for allylic sulfination with unactivated allylic alcohols,
Org. Lett. 2020, 22, 4893.

12. Peizhong Xie *, Zuolian Sun, Shuangshuang Li, Lei Zhang, Xinying Cai, Weishan Fu, Xiaobo Yang, Yanan Liu, Xiangyang Wo_, Teck-Peng Loh*, Dehydrative cross-coupling of allylic alcohols with alkynes,
Org. Lett. 2020, 22, 1599.

11. Peizhong Xie*, Shuangshuang Li, Yanan Liu, Xinying Cai, Jinyu Wang, Xiaobo Yang, Teck-Peng Loh*, Alkaline-earth metal-catalyzed dehydrative allylic alkylation.
Org. Lett. 2020, 22, 31.

10. Peizhong Xie*, Xiangyang Wo, Xiaobo Yang, Xinying Cai, Shuangshuang Li, Cuiqing Gao, Weishan Fu, Zuolian Sun, Teck-Peng Loh*, Calcium-catalyzed regioselective dehydrative cross-coupling of propargylic alcohols with 1,3-dicarbonyl compounds,
Green Chem. 2019, 21, 5207.

9. Peizhong Xie *, Weishan Fu, Xinying Cai, Zuolian Sun, Ying Wu, Shuangshuang Li, Cuiqing Gao, Xiaobo Yang, Teck-Peng Loh*, A Ba/Pd catalytic system enables dehydrative cross-coupling and excellent E-selective wittig reactions,
Org. Lett. 2019, 21, 7055.

8. Peizhong Xie*, Weishan Fu, Ying Wu, Xinying Cai, Zuolian Sun, Shuangshuang Li, Cuiqing Gao, Xiaobo Yang, Teck-Peng Loh*, Allylic phosphorus ylides directly generated from alcohols with water as the only byproduct,
Org. Lett. 2019, 21, 4168.

7. Peizhong Xie*, Jinyu Wang, Yanan Liu, Jing Fan, Xiangyang Wo, Weishan Fu, Zuolian Sun, Teck-Peng Loh*, Water-promoted C-S bond formation reactions,
Nat. Commun. 2018, 9, 1321. (Highlighted by K. J. Geogheghan, Nat. Rev. Chem. 2018, 2, 3).

6. Yanan Liu, Peizhong Xie*, Zuolian Sun, Xiangyang Wo, Cuiqing Gao, Weishan Fu, Teck-Peng Loh*, Direct substitution of secondary and tertiary alcohols to generate sulfones under catalyst and additive-free conditions,
Org. Lett. 2018, 20, 5353.

5. Peizhong Xie*, Jing Fan, Yanan Liu, Xiangyang Wo, Weishan Fu, Teck-Peng Loh*, Bronsted acid/organic photoredox cooperative catalysis: Easy access to tri- and tetra-substituted alkenylphosphorus compounds from alcohols and P-H species,
Org. Lett. 2018, 20, 3341.

4. Xiangyang Wo, Peizhong Xie*, Weishan Fu, Cuiqing Gao, Yanan Liu, Zuolian Sun, Teck-Peng Loh*, Barium-catalyzed C-OH/P-H dehydrative cross-coupling for C-P Bond construction,
Chem. Commun. 2018, 54, 11132.

3. Peizhong Xie*, Jinyu Wang, Jing Fan, Yanan Liu, Xiangyang Wo, Weishan Fu, Teck-Peng Loh*, The C–OH/P–H dehydrative cross-coupling for the construction of the P–C bond under metal free conditions,
Green Chem. 2017, 19, 2135.

2. Peizhong Xie *, Lei Guo, Lanlan Xu, Teck-Peng Loh*, Asymmetric P-C bond formation：diastereoselective synthesis of adjacent P,C-stereogenic allylic phosphorus compounds,
Chem. Asian J. 2016, 11, 1353.

1. Peizhong Xie, You Huang*, Morita-Baylis-Hillman adduct derivates (MBHADs): the versatile reactivity in Lewis base-promoted annulation,
Org. Biomol. Chem. 2015, 13, 8578. (Review, ESI Highly Cited Paper).