李 伟，博士，副教授，硕士生导师
Email: liwei93@njtech.edu.cn
个人简历：
2023.12 - 至今， 南京工业大学，化学与分子工程学院，副教授
2023.05 - 2023.10 湖南大学，化学化工学院，副研究员
2020.11 - 2023.10 湖南大学，化学化工学院，博士后
2015.09 - 2020.10 湖南大学，化学化工学院，理学博士(硕博)，导师：袁林教授
2011.09 - 2015.06 湖北理工学院，化学与化工学院，工学学士
研究方向：
围绕生物医学成像研究和体外诊断的需求，结合染料结构性能调控、生物分子识别策略与纳米功能化技术，开发高特异性、高灵敏的新型生物探针，为新型生物分子的精准检测与成像分析提供有力工具。
1）开发光学成像新平台、特异性识别策略，构建新型生物标志物的光学(荧光、余辉等)探针
2）光学探针的纳米功能化及其成像分析与诊疗应用研究
3）开发新型精准快速的化学生物传感器件，满足体外诊断与现场即时检测
学术成绩：
至今以第一作者（或共一）或通讯作者发表SCI论文20余篇，包括化学TOP期刊J. Am. Chem. Soc.、Angew. Chem. Int. Ed.及其他化学权威期刊（Coord. Chem. Rev.、Adv. Funct. Mater.、Chem. Sci.、Anal. Chem. (3篇)、ACS Sens.、Biosens. Bioelectron.、Chinese. Chem. Lett.(2篇)等。申请发明专利2项，获授权发明专利1项。
科研项目：
国家自然科学基金 青年基金项目（22404081），2024-2027，主持
江苏省自然科学基金 青年基金项目（BK20240534），2024-2027，主持
江苏省高等学校自然科学基金 面上项目（1020242423），2024-2026，主持
中国博士后科学基金面上项目（2025M770985），2025-2027，主持
2025年江苏省青年科技人才托举工程（JSTJ-2025-254），2025-2027，主持
代表性论文：(相关链接:ORCID iD https://orcid.org/0000-0001-6694-3368)
1）X. Liu‡, W. Li‡, Y. Shen, L. He, H. Lai, Y. Chen, L. Chen,* X.-B. Zhang, and L. Yuan*. Selective Twin NIR-IIb Ratiometric Luminescence Nanoprobes Enable the Accurate Visualization of MPO-Mediated Oxidative Stress in Acute Liver Injury. Advanced Functional Materials, 2025, 35, 2414772.
2）J. Zhou‡, X. Hu‡, C. Liu, Y. Liu, N. Tian, F. Wu, W. Li*, J. Lei, Z. Dai*. Lanthanide-bimetallic organic frameworks: from mechanism and sensors design to ratiometric fluorescent applications, Coordination Chemistry Reviews, 2025, 534, 216574.
3）Y. Shen‡, W. Li‡, Z. Zhou, J. Xu, Y.Li, H. Li, X. Zheng, S. Liu,* X.-B. Zhang, and L. Yuan*. Dual-Locked fluorescent probes activated by aminopeptidase N and the tumor redox environment for high-precision imaging of tumor boundaries. Angewandte Chemie International Edition, 2024, 63, e202406332.
4）X. Hu, C. Liu, J. Zhou, W. Li*, Z. Dai*. Advances in the recognition strategies and analytical techniques of bile acids, TrAC Trends in Analytical Chemistry, 2024, 180, 117894.
5）C. Liu, T. Zhao, J. Zhou, X. Hu, D. Pan, J. Li, W. Li*, Z. Dai*. Optical lateral flow immune assay technology for body fluid sensing. Chinese Chemical Letters, 2025, 110967.
6）X. Hou, Y. Xue, J. Yang, Z. Li, Z. Xu*, W. Li*, and L. Yuan*. A Cascade Activation Probe with Double-Enhanced Near-Infrared Imaging for Monitoring Peroxynitrite Fluctuations in Vivo. Analytical Chemistry, 2024, 96, 17657−17664
7）W. Li, S. Yin, Y. Shen, H. Li, L. Yuan,* and X.-B. Zhang*. Molecular engineering of pH-responsive NIR oxazine assemblies for evoking tumor ferroptosis via triggering lysosomal dysfunction. Journal of the American Chemical Society, 2023, 145, 6, 3736-3747.
8）Q. Wu‡, Q.-H. Zhou‡, W. Li*, T.-B. Ren, X.-. Zhang, and L. Yuan*. Evolving an ultra-sensitive near-infrared β-galactosidase fluorescent probe for breast cancer imaging and surgical resection navigation. ACS Sensors, 2022, 7, 3829-3837.
9）C. Peng, J. Yang, W. Li*, D. Lin, Y. Fei, X. Chen, L. Yuan, Y. Li*. Development of a high signal-to-noise probe based on the facile modification of xanthene dye for imaging peroxynitrite during liver ischemia and reperfusion process. Analytical Chemistry, 2022, 94, 10773-10780.
10）L. Su, F. Yang, W. Li*, H. Li, C. Wang, q. Wang*, L. Yuan*. Engineering a selective fluorescent sensor with high signal-to-background ratio for microalbumin detection and imaging. Materials Chemistry Frontiers, 2022, 6, 3084-3093.
11）W. Li, Y. Shen, X. Gong, X.-B. Zhang, and L. Yuan*. Highly selective fluorescent probe design for visualizing hepatic hydrogen sulfide in the pathological progression of nonalcoholic fatty liver. Analytical Chemistry, 2021, 93, 16673−16682.
12）W. Li‡, L. Wang‡, S. Yin, H. Lai, L. Yuan*, X. Zhang. Engineering a highly selective probe for ratiometric imaging of H2Sn and revealing its signaling pathway in fatty liver disease. Chemical Science, 2020, 11, 7991-7999.
13）W. Li, S. Yin, X. Gong, W. Xu, R. Yang, Y. Wan, L. Yuan*, X. Zhang. Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe. Chemical communications, 2020, 56, 1349-1352.
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