Electrospun polymeric nanofiber decorated with sea urchin-like gold nanoparticles as an efficient and stable SERS platform

Yaqin Sang, Xin Chen, Li Zhang, Dongyan Li, Hui Xu*

Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing Tech University, Nanjing 211816, China.

Abstract: Surface enhanced Raman scattering (SERS)-based nanoprobes have been used as well-established analytical tools enabling single-molecule detection. In this work, we report a facile method to decorate sea urchin-like gold nanoparticles (SUGNPs) on the surface of PMMA/P4VP nanofibers. Firstly, PMMA/P4VP nanofibers within the submicrometer size range were prepared by applying the electrospinning technique. Then, the incorporation of SUGNPs on the surface of PMMA/P4VP nanofiber was achieved by immersing PMMA/P4VP nanofiber into freshly prepared SUGNP aqueous solution through the specific Au-N interactions. The as-fabricated SUGNP-coated PMMA/P4VP nanofibers exhibited good sensitivity and reproducibility in SERS measurements with the relative standard deviation down to 6.6 %, by employing 4-mercaptobenzoic acid as a probe molecule with 30 min of soaking time. Hence, we envisage that the SUGNP-coated PMMA/P4VP nanofibers can act as efficient and stable SERS substrates for potential applications in molecular detection as well as chemical and biological analysis.

Journal of Colloid and Interface Science 590 (2021) 125–133.（IF=7.489）

文章链接：https://doi.org/10.1016/j.jcis.2021.01.036